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-Structure paper
Title | The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine. |
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Journal, issue, pages | Structure, Vol. 22, Page 1399-1407, Year 2014 |
Publish date | Jun 30, 2014 (structure data deposition date) |
Authors | Ulens, C. / Spurny, R. / Thompson, A.J. / Alqazzaz, M. / Debaveye, S. / Han, L. / Price, K. / Villalgordo, J.M. / Tresadern, G. / Lynch, J.W. / Lummis, S.C. |
External links | Structure / PubMed:25199693 |
Methods | X-ray diffraction |
Resolution | 3.2 - 3.901 Å |
Structure data | PDB-4twd: PDB-4twf: PDB-4twh: |
Chemicals | ChemComp-377: ChemComp-BR7: |
Source |
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Keywords | TRANSPORT PROTEIN / ELIC / LGIC / cys-loop / channel / memantine / pore blocker |