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TitleCrystal structure of a Homo sapiens hepatocytic transcription factor hB1F-2 (B1F2) in complex with nuclear receptor subfamily 0 group B member 1 (NR0B1, residues 140-154) from human at 1.86 A resolution
Journal, issue, pagesTo be published
Publish dateDec 5, 2014 (structure data deposition date)
AuthorsJoint Center for Structural Genomics (JCSG) / Partnership for Stem Cell Biology
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.859 Å
Structure data

PDB-4rwv:
Crystal structure of PIP3 bound human nuclear receptor LRH-1 (Liver Receptor Homolog 1, NR5A2) in complex with a co-regulator DAX-1 (NR0B1) peptide at 1.86 A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.859 Å

Chemicals

ChemComp-PIZ:
(2S)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Ligand-binding domain of nuclear hormone receptor / PF00104 family / Structural Genomics / Joint Center for Structural Genomics / JCSG / Protein Structure Initiative / PSI-BIOLOGY / Partnership for Stem Cell Biology / STEMCELL

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