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TitleCrystal structure of thymidine kinase from herpes simplex virus type 1 in complex with dF-EdU
Journal, issue, pagesTo be Published
Publish dateFeb 10, 2014 (structure data deposition date)
AuthorsPernot, L. / Neef, A.B. / Westermaier, Y. / Perozzo, R. / Luedtke, N. / Scapozza, L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-4oql:
Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with dF-EdU
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-F2U:
2'-deoxy-5-ethynyl-2',2'-difluorouridine

ChemComp-HOH:
WATER

Source
  • human herpesvirus 1 (Herpes simplex virus type 1)
KeywordsTRANSFERASE / DNA SYNTHESIS / THYMIDINE KINASE / ATP-BINDING / NUCLEOTIDE-BINDING / 5-ETHYNYLURIDINE NUCLEOSIDE DERIVATIVE

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