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-Structure paper
Title | Insights into mucopolysaccharidosis I from the structure and action of alpha-L-iduronidase. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 9, Page 739-745, Year 2013 |
Publish date | Apr 29, 2013 (structure data deposition date) |
Authors | Bie, H. / Yin, J. / He, X. / Kermode, A.R. / Goddard-Borger, E.D. / Withers, S.G. / James, M.N. |
External links | Nat. Chem. Biol. / PubMed:24036510 |
Methods | X-ray diffraction |
Resolution | 2.1 - 2.99 Å |
Structure data | PDB-4kgj: PDB-4kgl: PDB-4kh2: PDB-4mj2: PDB-4mj4: |
Chemicals | ChemComp-NAG: ChemComp-GOL: ChemComp-IDF: ChemComp-TLA: ChemComp-CL: ChemComp-HOH: ChemComp-IDJ: ChemComp-FIF: ChemComp-SRT: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / glycoside hydrolase family 39 / TIM barrel / beta sandwich / fibronectin III domain / glycosaminoglycans / HYDROLASE-HYDROLASE INHIBITOR complex / HYDROLASE / fibronectin type III / hydrolyze iduronic acids from the non-reducing ends of glycosaminoglycan / intracellular / lysosomal |