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Structure paper

TitleDeveloping isoform specific inhibitors against hCAIX using CAIX mimic
Journal, issue, pagesTo be Published
Publish dateApr 4, 2013 (structure data deposition date)
AuthorsBiswas, S. / West, D. / Pinard, M. / McKenna, R.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.802 Å
Structure data

PDB-4k0s:
Structure of HCAIX mimic (HCAII with 5 mutations in active site) in complex with acetazolamide
Method: X-RAY DIFFRACTION / Resolution: 1.802 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-AZM:
5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE / medication*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / alpha beta fold

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