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-Structure paper
Title | Evaluation of Cancer Dependence and Druggability of PRP4 Kinase Using Cellular, Biochemical, and Structural Approaches. |
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Journal, issue, pages | J. Biol. Chem., Vol. 288, Page 30125-30138, Year 2013 |
Publish date | Dec 6, 2012 (structure data deposition date) |
Authors | Gao, Q. / Mechin, I. / Kothari, N. / Guo, Z. / Deng, G. / Haas, K. / McManus, J. / Hoffmann, D. / Wang, A. / Wiederschain, D. ...Gao, Q. / Mechin, I. / Kothari, N. / Guo, Z. / Deng, G. / Haas, K. / McManus, J. / Hoffmann, D. / Wang, A. / Wiederschain, D. / Rocnik, J. / Czechtizky, W. / Chen, X. / McLean, L. / Arlt, H. / Harper, D. / Liu, F. / Majid, T. / Patel, V. / Lengauer, C. / Garcia-Echeverria, C. / Zhang, B. / Cheng, H. / Dorsch, M. / Huang, S.M. |
External links | J. Biol. Chem. / PubMed:24003220 |
Methods | X-ray diffraction |
Resolution | 2 - 2.44 Å |
Structure data | PDB-4ian: PDB-4ifc: PDB-4iir: PDB-4ijp: |
Chemicals | ChemComp-SO4: ChemComp-HOH: ChemComp-ADP: ChemComp-ANP: ChemComp-MG: ChemComp-1EH: |
Source |
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Keywords | TRANSFERASE / kinase / TRANSFERASE/TRANSFERASE INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR complex |