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-Structure paper
Title | Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents. |
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Journal, issue, pages | Science, Vol. 339, Page 587-590, Year 2013 |
Publish date | Nov 28, 2012 (structure data deposition date) |
Authors | Prota, A.E. / Bargsten, K. / Zurwerra, D. / Field, J.J. / Diaz, J.F. / Altmann, K.H. / Steinmetz, M.O. |
External links | Science / PubMed:23287720 |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.3 Å |
Structure data | PDB-4i4t: PDB-4i50: PDB-4i55: |
Chemicals | ChemComp-GTP: ChemComp-MG: ChemComp-CA: ChemComp-CL: ChemComp-GOL: ChemComp-GDP: ChemComp-TYR: ChemComp-MES: ChemComp-ZPN: ChemComp-ACP: ChemComp-HOH: ChemComp-EP: |
Source |
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Keywords | CELL CYCLE / Alpha-tubulin / beta-tubulin / ligase / GTPase / stathmin / zamanolide / microtubule / epothilone A |