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-Structure paper
Title | Structural insight into potent broad-spectrum inhibition with reversible recyclization mechanism: avibactam in complex with CTX-M-15 and Pseudomonas aeruginosa AmpC beta-lactamases |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 57, Page 2496-2505, Year 2013 |
Publish date | Sep 6, 2012 (structure data deposition date) |
![]() | Lahiri, S.D. / Mangani, S. / Durand-Reville, T. / Benvenuti, M. / De Luca, F. / Sanyal, G. / Docquier, J.D. |
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Methods | X-ray diffraction |
Resolution | 1.1 - 1.86 Å |
Structure data | ![]() PDB-4gzb: ![]() PDB-4hbt: ![]() PDB-4hbu: ![]() PDB-4hef: |
Chemicals | ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-SO4: ![]() ChemComp-CL: ![]() ChemComp-NXL: ![]() ChemComp-GOL: |
Source |
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![]() | HYDROLASE / beta-lactamase fold / antibiotic resistance / Hydrolysis of beta-lactams / HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR complex / b-lactamase / periplasmic protein |