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Structure paper

TitleStructure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity
Journal, issue, pagesTo be Published
Publish dateJun 28, 2012 (structure data deposition date)
AuthorsBorbulevych, O.Y. / Baker, B.M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.74 Å
Structure data

PDB-4ftv:
The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide
Method: X-RAY DIFFRACTION / Resolution: 2.74 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human t-cell lymphotropic virus type 1 (african isolate)
KeywordsIMMUNE SYSTEM / TAX peptide / nonapeptide / MHC class I / HLA-A2 / TCR A6 / cross-reactivity / high affinity / c134

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