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-Structure paper
Title | Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding |
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Journal, issue, pages | Immunity, Vol. 36, Page 1073-1086, Year 2012 |
Publish date | Mar 29, 2012 (structure data deposition date) |
![]() | Ouyang, S. / Song, X. / Wang, Y. / Ru, H. / Shaw, N. / Jiang, Y. / Niu, F. / Zhu, Y. / Qiu, W. / Parvatiyar, K. ...Ouyang, S. / Song, X. / Wang, Y. / Ru, H. / Shaw, N. / Jiang, Y. / Niu, F. / Zhu, Y. / Qiu, W. / Parvatiyar, K. / Li, Y. / Zhang, R. / Cheng, G. / Liu, Z.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.147 - 2.45 Å |
Structure data | ![]() PDB-4ef4: ![]() PDB-4ef5: |
Chemicals | ![]() ChemComp-C2E: ![]() ChemComp-CA: ![]() ChemComp-HOH: |
Source |
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![]() | IMMUNE SYSTEM / STING/MITA/ERIS/MPYS/TMEM173 / innate immune system / type I interferon / dimerization / c-di-GMP / 5 helices and 5 strands in single domain |