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-Structure paper
Title | An aminoquinazoline inhibitor of the essential bacterial cell wall synthetic enzyme GlmU has a unique non-protein-kinase-like binding mode. |
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Journal, issue, pages | Biochem. J., Vol. 446, Page 405-413, Year 2012 |
Publish date | Mar 6, 2012 (structure data deposition date) |
Authors | Larsen, N.A. / Nash, T.J. / Morningstar, M. / Shapiro, A.B. / Joubran, C. / Blackett, C.J. / Patten, A.D. / Boriack-Sjodin, P.A. / Doig, P. |
External links | Biochem. J. / PubMed:22721802 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-4e1k: |
Chemicals | ChemComp-SO4: ChemComp-PG4: ChemComp-0N5: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / peptidoglycan synthesis / cell shape / metal-binding / cell wall biogenesis/degradation / multifunctional enzyme / acyltransferase / uridyltransferase / Nucleotidyl transferase / TRANSFERASE-TRANSFERASE INHIBITOR complex |