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-Structure paper
Title | Identifying a Novel Series of Pfkfb3 Inhibitors as a Metabolic Approach to Treating Cancer from Hts, Biophysical and Biochemical Methods |
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Journal, issue, pages | To be Published |
Publish date | Oct 29, 2014 (structure data deposition date) |
Authors | Stgallay, S.A. / Bennett, N. / Critchlow, S. / Davies, G. / Debreczeni, J.E. / Evans, N. / Holdgate, G. / Jones, N.P. / Leach, L. / Maman, S. ...Stgallay, S.A. / Bennett, N. / Critchlow, S. / Davies, G. / Debreczeni, J.E. / Evans, N. / Holdgate, G. / Jones, N.P. / Leach, L. / Maman, S. / Mcloughlin, S. / Preston, M. / Rigoreau, L. / Thomas, A. / Walker, G. / Walsch, J. / Ward, R.A. / Wheatley, E. / Winter, J. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.32 - 3.24 Å |
Structure data | PDB-4d4j: PDB-4d4k: PDB-4d4l: PDB-4d4m: |
Chemicals | ChemComp-PO4: ChemComp-PHS: ChemComp-F6P: ChemComp-BKI: ChemComp-HOH: ChemComp-BKE: ChemComp-BKS: ChemComp-BKV: |
Source |
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Keywords | TRANSFERASE / SUGAR KINASE / WARBURG EFFECT / ONCOLOGY |