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-Structure paper
Title | Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 110, Page 20479-, Year 2013 |
Publish date | Oct 21, 2013 (structure data deposition date) |
![]() | Hill, C.H. / Graham, S.C. / Read, R.J. / Deane, J.E. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.97 - 2.09 Å |
Structure data | ![]() PDB-4ccc: ![]() PDB-4ccd: ![]() PDB-4cce: |
Chemicals | ![]() ChemComp-147: ![]() ChemComp-NAG: ![]() ChemComp-CA: ![]() ChemComp-HOH: ![]() ChemComp-2DG: ![]() ChemComp-GAL: |
Source |
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![]() | HYDROLASE / KRABBE DISEASE / GLYCOSYL HYDROLASE / 4-NITROPHENYL-BETA-D-GALACTOPYRANOSIDE / LYSOSOMAL STORAGE DISEASE / ENZYME- SUBSTRATE COMPLEX / GALACTOSIDASE / D-GALACTAL / ENZYME-INTERMEDIATE COMPLEX / ENZYME-PRODUCT COMPLEX |