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TitleEif4E3 Acts as a Tumor Suppressor by Utilizing an Atypical Mode of Methyl-7-Guanosine CAP Recognition
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 110, Page 3877-, Year 2013
Publish dateAug 15, 2012 (structure data deposition date)
AuthorsOsborne, M.J. / Volpon, L. / Kornblatt, J.A. / Culjkovic-Kraljcic, B. / Baguet, A. / Borden, K.L.B.
External linksProc. Natl. Acad. Sci. USA / PubMed:23431134
MethodsNMR (solution)
Structure data

PDB-4b6u:
Solution structure of eIF4E3 in complex with m7GDP
Method: SOLUTION NMR

PDB-4b6v:
The third member of the eIF4E family represses gene expression via a novel mode of recognition of the methyl-7 guanosine cap moiety
Method: SOLUTION NMR

Chemicals

ChemComp-M7G:
7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE

Source
  • mus musculus (house mouse)
KeywordsTRANSLATION / M7G CAP

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