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-Structure paper
Title | 5-(2-Amino-Pyrimidin-4-Yl)-1H-Pyrrole and 2-(2-Amino-Pyrimidin-4-Yl)-1,5,6,7-Tetrahydro-Pyrrolo[3,2-C]Pyridin-4-One Derivatives as New Classes of Selective and Orally Available Polo-Like Kinase 1 Inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 22, Page 96-, Year 2012 |
Publish date | Oct 17, 2011 (structure data deposition date) |
![]() | Caruso, M. / Valsasina, B. / Ballinari, D. / Bertrand, J.A. / Brasca, M.G. / Caldarelli, M. / Cappella, P. / Fiorentini, F. / Gianellini, L.M. / Scolaro, A. / Beria, I. |
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Methods | X-ray diffraction |
Resolution | 2.35 - 2.7 Å |
Structure data | ![]() PDB-4a4l: ![]() PDB-4a4o: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-TLA: ![]() ChemComp-939: ![]() ChemComp-HOH: ![]() ChemComp-664: |
Source |
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![]() | TRANSFERASE |