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-Structure paper
Title | Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 21, Page 7612-7623, Year 2013 |
Publish date | Sep 4, 2013 (structure data deposition date) |
![]() | Hamaguchi, W. / Masuda, N. / Isomura, M. / Miyamoto, S. / Kikuchi, S. / Amano, Y. / Honbou, K. / Mihara, T. / Watanabe, T. |
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Methods | X-ray diffraction |
Resolution | 2.26 Å |
Structure data | ![]() PDB-3wi2: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-MG: ![]() ChemComp-P98: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / phosphodiesterase / cGMP binding / HYDROLASE-HYDROLASE INHIBITOR complex |