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-Structure paper
Title | Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 8, Page 366-374, Year 2012 |
Publish date | Oct 10, 2011 (structure data deposition date) |
![]() | Georghiou, G. / Kleiner, R.E. / Pulkoski-Gross, M. / Liu, D.R. / Seeliger, M.A. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.241 Å |
Structure data | ![]() PDB-3u4w: ![]() PDB-3u51: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / protein kinase / Src-like inactive conformation / TRANSFERASE-TRANSFERASE INHIBITOR complex |