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Structure paper

TitleStructural basis for nematode eIF4E binding an m2,2,7G-Cap and its implications for translation initiation.
Journal, issue, pagesNucleic Acids Res., Vol. 39, Page 8820-8832, Year 2011
Publish dateMar 19, 2010 (structure data deposition date)
AuthorsLiu, W. / Jankowska-Anyszka, M. / Piecyk, K. / Dickson, L. / Wallace, A. / Niedzwiecka, A. / Stepinski, J. / Stolarski, R. / Darzynkiewicz, E. / Kieft, J. ...Liu, W. / Jankowska-Anyszka, M. / Piecyk, K. / Dickson, L. / Wallace, A. / Niedzwiecka, A. / Stepinski, J. / Stolarski, R. / Darzynkiewicz, E. / Kieft, J. / Zhao, R. / Jones, D.N. / Davis, R.E.
External linksNucleic Acids Res. / PubMed:21965542
MethodsX-ray diffraction
Resolution2.05 - 2.9 Å
Structure data

PDB-3m93:
Complex crystal structure of Ascaris suum eIF4E-3 with m7G cap
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-3m94:
Complex crystal structure of Ascaris suum eIF4E-3 with m2,2,7G cap
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-M7G:
7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-M7M:
N,N,7-trimethylguanosine 5'-(trihydrogen diphosphate)

ChemComp-ACE:
ACETYL GROUP

Source
  • ascaris suum (pig roundworm)
  • homo sapiens (human)
KeywordsTRANSLATION / eIF4E / Berkeley Structural Genomics Center / BSGC

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