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-Structure paper
Title | The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: the carbonic anhydrase I-topiramate complex. |
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Journal, issue, pages | Org. Biomol. Chem., Year 2010 |
Publish date | Feb 25, 2010 (structure data deposition date) |
![]() | Alterio, V. / Monti, S.M. / Truppo, E. / Pedone, C. / Supuran, C.T. / De Simone, G. |
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Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | ![]() PDB-3lxe: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-TOR: ![]() ChemComp-HOH: |
Source |
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![]() | LYASE / carbonic anhydrase 1 / topiramate / enzyme-inhibitor complex |