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Structure paper

TitleInsights into the molecular inactivation mechanism of human activated thrombin-activatable fibrinolysis inhibitor
Journal, issue, pagesJ. Thromb. Haemost., Vol. 8, Page 1056-1065, Year 2010
Publish dateFeb 1, 2010 (structure data deposition date)
AuthorsSanglas, L. / Arolas, J.L. / Valnickova, Z. / Aviles, F.X. / Enghild, J.J. / Gomis-Ruth, F.X.
External linksJ. Thromb. Haemost. / PubMed:20088943
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-3lms:
Structure of human activated thrombin-activatable fibrinolysis inhibitor, TAFIa, in complex with tick-derived funnelin inhibitor, TCI.
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GLY:
GLYCINE

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • rhipicephalus bursa (arthropod)
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / fibrinolysis / cogaulation / funnelin / alpha-beta-hydrolase / metallopeptidase / Alternative splicing / Carboxypeptidase / Disulfide bond / Glycoprotein / Hydrolase / Metal-binding / Metalloprotease / Polymorphism / Protease / Secreted / Zinc / Zymogen / Blood coagulation / Metalloenzyme inhibitor / Metalloprotease inhibitor / HYDROLASE-HYDROLASE INHIBITOR complex

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