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-Structure paper
Title | Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD. |
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Journal, issue, pages | Chem. Biol., Vol. 16, Page 849-861, Year 2009 |
Publish date | Aug 5, 2008 (structure data deposition date) |
Authors | Sorci, L. / Pan, Y. / Eyobo, Y. / Rodionova, I. / Huang, N. / Kurnasov, O. / Zhong, S. / MacKerell, A.D. / Zhang, H. / Osterman, A.L. |
External links | Chem. Biol. / PubMed:19716475 |
Methods | X-ray diffraction |
Resolution | 2.02 - 2.2 Å |
Structure data | PDB-3e27: PDB-3hfj: |
Chemicals | ChemComp-DND: ChemComp-MG: ChemComp-HOH: ChemComp-DZ9: ChemComp-CA: |
Source |
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Keywords | TRANSFERASE / Rossman-like fold / nucleotide-binding motif / Nucleotidyltransferase / enzyme-inhibitor complex / NAD / Pyridine nucleotide biosynthesis |