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-Structure paper
Title | Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. |
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Journal, issue, pages | Protein Sci., Vol. 18, Page 1107-1114, Year 2009 |
Publish date | Feb 19, 2009 (structure data deposition date) |
![]() | Afshar, S. / Sawaya, M.R. / Morrison, S.L. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.52 Å |
Structure data | ![]() PDB-3gb9: ![]() PDB-3ggs: |
Chemicals | ![]() ChemComp-A2F: ![]() ChemComp-SO4: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-2FD: |
Source |
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![]() | TRANSFERASE / Enzyme-product complex / Disease mutation / Glycosyltransferase / enzyme-prodrug complex |