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-Structure paper
Title | Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems. |
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Journal, issue, pages | Faseb J., Vol. 23, Page 2735-2740, Year 2009 |
Publish date | Nov 7, 2008 (structure data deposition date) |
Authors | Zhang, H. / Astrof, N.S. / Liu, J.H. / Wang, J.H. / Shimaoka, M. |
External links | Faseb J. / PubMed:19332643 |
Methods | X-ray diffraction |
Resolution | 1.6 - 1.7 Å |
Structure data | PDB-3f74: PDB-3f78: |
Chemicals | ChemComp-GOL: ChemComp-MG: ChemComp-HOH: ChemComp-ICF: |
Source |
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Keywords | CELL ADHESION / integrin / LFA1 / I domain / inactive conformation / wild type / Glycoprotein / Magnesium / Membrane / Receptor / Transmembrane / volatile anesthetic / isoflurane / inhibitor of integrin |