+Search query
-Structure paper
Title | The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism. |
---|---|
Journal, issue, pages | Biochemistry, Vol. 47, Page 8261-8270, Year 2008 |
Publish date | Feb 20, 2008 (structure data deposition date) |
![]() | Faucher, F. / Cantin, L. / Luu-The, V. / Labrie, F. / Breton, R. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.9 Å |
Structure data | ![]() PDB-3cav: |
Chemicals | ![]() ChemComp-NAP: ![]() ChemComp-CI2: ![]() ChemComp-BME: ![]() ChemComp-EDO: ![]() ChemComp-HOH: |
Source |
|
![]() | OXIDOREDUCTASE / 5b-reductase / 5beta-reductase / 5b-red / AKR1D1 / AKR / aldo-keto reductase / NADP / androstenedione. NADPH / Bile acid catabolism / Cytoplasm / Disease mutation / Lipid metabolism / Steroid metabolism |