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TitleA New Autocatalytic Activation Mechanism for Cysteine Proteases Revealed by Prevotella intermedia Interpain A
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 2871-2882, Year 2008
Publish dateNov 9, 2007 (structure data deposition date)
AuthorsMallorqui-Fernandez, N. / Manandhar, S.P. / Mallorqui-Fernandez, G. / Uson, I. / Wawrzonek, K. / Kantyka, T. / Sola, M. / Thogersen, I.B. / Enghild, J.J. / Potempa, J. / Gomis-Ruth, F.X.
External linksJ. Biol. Chem. / PubMed:17993455
MethodsX-ray diffraction
Resolution1.5 - 3.2 Å
Structure data

PDB-3bb7:
Structure of Prevotella intermedia prointerpain A fragment 39-359 (mutant C154A)
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-3bba:
Structure of active wild-type Prevotella intermedia interpain A cysteine protease
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • prevotella intermedia (bacteria)
KeywordsHYDROLASE / cysteine protease / zymogen activation / bacterial odontopathogen / Prevotella intermedia

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