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-Structure paper
Title | Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding |
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Journal, issue, pages | J. Biol. Chem., Vol. 283, Page 17531-17541, Year 2008 |
Publish date | Oct 25, 2007 (structure data deposition date) |
Authors | Bashiri, G. / Squire, C.J. / Moreland, N.J. / Baker, E.N. |
External links | J. Biol. Chem. / PubMed:18434308 |
Methods | X-ray diffraction |
Resolution | 1.9 - 1.95 Å |
Structure data | PDB-3b4y: PDB-3c8n: |
Chemicals | ChemComp-F42: ChemComp-FLC: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / TIM-barrel / non-prolyl cis-peptide bulge / F420 binding / Structural Genomics / TB Structural Genomics Consortium / TBSGC / TIM barrel / non-prolyl cis-peptide |