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-Structure paper
Title | Truncation and Optimisation of Peptide Inhibitors of Cyclin-Dependent Kinase 2-Cyclin a Through Structure-Guided Design. |
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Journal, issue, pages | Chemmedchem, Vol. 4, Page 1120-, Year 2009 |
Publish date | Apr 1, 2009 (structure data deposition date) |
Authors | Kontopidis, G. / Andrews, M.J. / Mcinnes, C. / Plater, A. / Innes, L. / Renachowski, S. / Cowan, A. / Fischer, P.M. |
External links | Chemmedchem / PubMed:19472269 |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.9 Å |
Structure data | PDB-2wev: PDB-2wfy: PDB-2whb: |
Chemicals | ChemComp-CK7: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / CDK2 / KINASE / CYCLIN / ACTIVE / NUCLEUS / MITOSIS / SERINE/THREONINE-PROTEIN KINASE / CYTOPLASM / INHIBITION / CELL CYCLE / ATP-BINDING / CELL DIVISION / PHOSPHOPROTEIN / NUCLEOTIDE-BINDING / POLYMORPHISM / BETA-PEPTIDE / CYCLIN GROOVE |