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-Structure paper
Title | Imidazoles: Sar and Development of a Potent Class of Cyclin-Dependent Kinase Inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 18, Page 5487-, Year 2008 |
Publish date | Aug 8, 2008 (structure data deposition date) |
Authors | Anderson, M. / Andrews, D.M. / Barker, A.J. / Brassington, C.A. / Breed, J. / Byth, K.F. / Culshaw, J.D. / Finlay, M.R. / Fisher, E. / Mcmiken, H.H. ...Anderson, M. / Andrews, D.M. / Barker, A.J. / Brassington, C.A. / Breed, J. / Byth, K.F. / Culshaw, J.D. / Finlay, M.R. / Fisher, E. / Mcmiken, H.H. / Green, C.P. / Heaton, D.W. / Nash, I.A. / Newcombe, N.J. / Oakes, S.E. / Pauptit, R.A. / Roberts, A. / Stanway, J.J. / Thomas, A.P. / Tucker, J.A. / Walker, M. / Weir, H.M. |
External links | Bioorg. Med. Chem. Lett. / PubMed:18815031 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.04 Å |
Structure data | PDB-2w05: PDB-2w06: |
Chemicals | ChemComp-FRT: ChemComp-HOH: ChemComp-FRV: |
Source |
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Keywords | TRANSFERASE / KINASE / MITOSIS / CELL CYCLE / SERINE/THREONINE-PROTEIN KINASE / ATP-BINDING / POLYMORPHISM / CELL DIVISION / PHOSPHOPROTEIN / PHOSPHORYLATION / NUCLEOTIDE-BINDING |