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-Structure paper
Title | Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration. |
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Journal, issue, pages | J. Exp. Med., Vol. 204, Page 2277-, Year 2007 |
Publish date | Mar 22, 2007 (structure data deposition date) |
Authors | Prosser, B.E. / Johnson, S. / Roversi, P. / Herbert, A.P. / Blaum, B.S. / Tyrrell, J. / Jowitt, T.A. / Clark, S.J. / Tarelli, E. / Uhrin, D. ...Prosser, B.E. / Johnson, S. / Roversi, P. / Herbert, A.P. / Blaum, B.S. / Tyrrell, J. / Jowitt, T.A. / Clark, S.J. / Tarelli, E. / Uhrin, D. / Barlow, P.N. / Sim, R.B. / Day, A.J. / Lea, S.M. |
External links | J. Exp. Med. / PubMed:17893204 |
Methods | X-ray diffraction |
Resolution | 2.35 - 2.5 Å |
Structure data | PDB-2uwn: PDB-2v8e: |
Chemicals | ChemComp-ACT: ChemComp-CL: ChemComp-SO4: ChemComp-HOH: ChemComp-GOL: |
Source |
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Keywords | IMMUNE SYSTEM / ALTERNATIVE SPLICING / SUCROSE OCTASULPHATE / AGE-RELATED MACULAR DEGENERATION / COMPLEMENT ALTERNATE PATHWAY / DISEASE MUTATION / GLYCOSAMINOGLYCAN / GLYCOPROTEIN / INNATE IMMUNITY / IMMUNE RESPONSE / SUSHI / FACTOR H / COMPLEMENT / POLYMORPHISM / SECRETED |