+Search query
-Structure paper
Title | Rapid Evolution of 6-Phenylpurine Inhibitors of Protein Kinase B Through Structure-Based Design |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 50, Page 2289-, Year 2007 |
Publish date | Mar 15, 2007 (structure data deposition date) |
Authors | Donald, A. / Mchardy, T. / Rowlands, M.G. / Hunter, L.J. / Davies, T.G. / Berdini, V. / Boyle, R.G. / Aherne, G.W. / Garrett, M.D. / Collins, I. |
External links | J. Med. Chem. / PubMed:17451235 |
Methods | X-ray diffraction |
Resolution | 1.94 - 2 Å |
Structure data | PDB-2uvx: PDB-2uvy: PDB-2uvz: PDB-2uw0: |
Chemicals | ChemComp-GVH: ChemComp-HOH: ChemComp-GVI: ChemComp-GVJ: ChemComp-GVK: |
Source |
|
Keywords | TRANSFERASE/INHIBITOR / CAMP / KINASE / MYRISTATE / TRANSFERASE / LIPOPROTEIN / SERINE/THREONINE-PROTEIN KINASE / TRANSFERASE-INHIBITOR COMPLEX / NUCLEOTIDE-BINDING / PROTEIN KINASE INHIBITOR / ATP- BINDING / NUCLEAR PROTEIN / PHOSPHORYLATION / ATP-BINDING |