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-Structure paper
Title | Synthesis, structural analysis, and SAR studies of triazine derivatives as potent, selective Tie-2 inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 17, Page 2886-2889, Year 2007 |
Publish date | Jan 25, 2007 (structure data deposition date) |
Authors | Hodous, B.L. / Geuns-Meyer, S.D. / Hughes, P.E. / Albrecht, B.K. / Bellon, S. / Caenepeel, S. / Cee, V.J. / Chaffee, S.C. / Emery, M. / Fretland, J. ...Hodous, B.L. / Geuns-Meyer, S.D. / Hughes, P.E. / Albrecht, B.K. / Bellon, S. / Caenepeel, S. / Cee, V.J. / Chaffee, S.C. / Emery, M. / Fretland, J. / Gallant, P. / Gu, Y. / Johnson, R.E. / Kim, J.L. / Long, A.M. / Morrison, M. / Olivieri, P.R. / Patel, V.F. / Polverino, A. / Rose, P. / Wang, L. / Zhao, H. |
External links | Bioorg. Med. Chem. Lett. / PubMed:17350837 |
Methods | X-ray diffraction |
Resolution | 2.2 - 2.8 Å |
Structure data | PDB-2oo8: PDB-2osc: |
Chemicals | ChemComp-RAJ: ChemComp-HOH: ChemComp-MUH: |
Source |
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Keywords | TRANSFERASE / Kinase / Kinase domain Tie-2 |