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-Structure paper
Title | Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides. |
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Journal, issue, pages | J. Med. Chem., Vol. 50, Page 3004-3014, Year 2007 |
Publish date | Oct 24, 2006 (structure data deposition date) |
![]() | Sabini, E. / Hazra, S. / Konrad, M. / Lavie, A. |
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Methods | X-ray diffraction |
Resolution | 1.7 - 1.91 Å |
Structure data | ![]() PDB-2no0: ![]() PDB-2no1: ![]() PDB-2no6: ![]() PDB-2no7: |
Chemicals | ![]() ChemComp-ADP: ![]() ChemComp-GEO: ![]() ChemComp-HOH: ![]() ChemComp-DCZ: ![]() ChemComp-ETV: ![]() ChemComp-LDC: |
Source |
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![]() | TRANSFERASE / dCK / gemcitabine / human deoxycytidine kinase / D-dC / emtricitabine / FTC / enantiomer / antiviral / L-dC / enantioselectivity |