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-Structure paper
Title | Allosteric Fbpase Inhibitors Gain 10(5) Times in Potency When Simultaneously Binding Two Neighboring AMP Sites. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 18, Page 4708-, Year 2008 |
Publish date | Apr 9, 2008 (structure data deposition date) |
![]() | Hebeisen, P. / Kuhn, B. / Kohler, P. / Gubler, M. / Huber, W. / Kitas, E. / Schott, B. / Benz, J. / Joseph, C. / Ruf, A. |
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Methods | X-ray diffraction |
Resolution | 2 - 2.2 Å |
Structure data | ![]() PDB-2jjk: ![]() PDB-2vt5: |
Chemicals | ![]() ChemComp-R15: ![]() ChemComp-HOH: ![]() ChemComp-ROK: |
Source |
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![]() | HYDROLASE / HYDROLASE (PHOSPHORIC MONOESTER) / DISEASE MUTATION / ALLOSTERIC ENZYME / ZINC / POLYMORPHISM / GLUCONEOGENESIS / CARBOHYDRATE METABOLISM |