+Search query
-Structure paper
Title | Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 16, Page 5659-5663, Year 2006 |
Publish date | Jun 25, 2006 (structure data deposition date) |
Authors | Hopkins, C.R. / O'neil, S.V. / Laufersweiler, M.C. / Wang, Y. / Pokross, M. / Mekel, M. / Evdokimov, A. / Walter, R. / Kontoyianni, M. / Petrey, M.E. ...Hopkins, C.R. / O'neil, S.V. / Laufersweiler, M.C. / Wang, Y. / Pokross, M. / Mekel, M. / Evdokimov, A. / Walter, R. / Kontoyianni, M. / Petrey, M.E. / Sabatakos, G. / Roesgen, J.T. / Richardson, E. / Demuth Jr., T.P. |
External links | Bioorg. Med. Chem. Lett. / PubMed:16919947 |
Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | PDB-2hfp: |
Chemicals | ChemComp-NSI: ChemComp-HOH: |
Source |
|
Keywords | TRANSCRIPTION / PPAR PPARGamma LBD |