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Title | NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design. |
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Journal, issue, pages | J. Mol. Biol., Vol. 360, Page 1-6, Year 2006 |
Publish date | Apr 19, 2006 (structure data deposition date) |
![]() | Sampathkumar, P. / Turley, S. / Sibley, C.H. / Hol, W.G. |
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Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | ![]() PDB-2gq2: |
Chemicals | ![]() ChemComp-IOD: ![]() ChemComp-K: ![]() ChemComp-NAP: ![]() ChemComp-PGE: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / M.TUBERCULOSIS / THYX / FDTS / TSCP / Flavin dependent Thymidylate synthase / inhibitor design / bivalent drugs |