+Search query
-Structure paper
Title | Crystal Structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in Complex with the 20S Proteasome Reveal Important Consequences of beta-Lactone Ring Opening and a Mechanism for Irreversible Binding. |
---|---|
Journal, issue, pages | J. Am. Chem. Soc., Vol. 128, Page 5136-5141, Year 2006 |
Publish date | Dec 7, 2005 (structure data deposition date) |
![]() | Groll, M. / Huber, R. / Potts, B.C. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | ![]() PDB-2fak: |
Chemicals | ![]() ChemComp-SA1: ![]() ChemComp-HOH: |
Source |
|
![]() | HYDROLASE / proteasome / ubiquitin / drug design / inhibitor / protease |