+Search query
-Structure paper
Title | Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 49, Page 5939-5946, Year 2006 |
Publish date | Jun 16, 2005 (structure data deposition date) |
Authors | Bosch, J. / Robien, M.A. / Mehlin, C. / Boni, E. / Riechers, A. / Buckner, F.S. / Van Voorhis, W.C. / Myler, P.J. / Worthey, E.A. / DeTitta, G. ...Bosch, J. / Robien, M.A. / Mehlin, C. / Boni, E. / Riechers, A. / Buckner, F.S. / Van Voorhis, W.C. / Myler, P.J. / Worthey, E.A. / DeTitta, G. / Luft, J.R. / Lauricella, A. / Gulde, S. / Anderson, L.A. / Kalyuzhniy, O. / Neely, H.M. / Ross, J. / Earnest, T.N. / Soltis, M. / Schoenfeld, L. / Zucker, F. / Merritt, E.A. / Fan, E. / Verlinde, C.L. / Hol, W.G.J. |
External links | J. Med. Chem. / PubMed:17004709 |
Methods | X-ray diffraction |
Resolution | 1.5 - 1.8 Å |
Structure data | PDB-2a0k: PDB-2f2t: PDB-2f62: PDB-2f64: PDB-2f67: |
Chemicals | ChemComp-SO4: ChemComp-GOL: ChemComp-HOH: ChemComp-5IQ: ChemComp-12M: ChemComp-12Q: ChemComp-12B: |
Source |
|
Keywords | TRANSFERASE / SGPP / Structural GENOMICS / PSI / PROTEIN STRUCTURE INITIATIVE / Nucleoside 2-deoxyribosyltransferase / Structural Genomics of Pathogenic Protozoa Consortium / PROTEIN STRUCTURE INITIATIVE NDRT / Trypanosoma brucei |