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-Structure paper
Title | Design, synthesis, and biological activity of non-basic compounds as factor Xa inhibitors: SAR study of S1 and aryl binding sites |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 13, Page 3927-3954, Year 2005 |
Publish date | Nov 29, 2004 (structure data deposition date) |
Authors | Komoriya, S. / Haginoya, N. / Kobayashi, S. / Nagata, T. / Mochizuki, A. / Suzuki, M. / Yoshino, T. / Horino, H. / Nagahara, T. / Isobe, Y. / Furugoori, T. |
External links | Bioorg. Med. Chem. / PubMed:15911309 |
Methods | X-ray diffraction |
Resolution | 2.2 - 2.3 Å |
Structure data | PDB-1wu1: PDB-2d1j: |
Chemicals | ChemComp-CA: ChemComp-D91: ChemComp-HOH: ChemComp-D01: |
Source |
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Keywords | HYDROLASE / glycoprotein / serine protease / plasma / blood coagulation factor / protein inhibitor complex / calcium-binding |