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-Structure paper
Title | Fragment-Based Lead Discovery Using X-Ray Crystallography |
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Journal, issue, pages | J. Med. Chem., Vol. 48, Page 403-, Year 2005 |
Publish date | Sep 2, 2004 (structure data deposition date) |
Authors | Hartshorn, M.J. / Murray, C.W. / Cleasby, A. / Frederickson, M. / Tickle, I.J. / Jhoti, H. |
External links | J. Med. Chem. / PubMed:15658854 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.214 Å |
Structure data | PDB-1w7h: PDB-1wax: PDB-1way: PDB-1wbg: PDB-1wbo: PDB-1wbu: PDB-1wcc: |
Chemicals | ChemComp-3IP: ChemComp-HOH: ChemComp-MG: ChemComp-LO1: ChemComp-L02: ChemComp-DMS: ChemComp-L03: ChemComp-2CH: ChemComp-WBU: ChemComp-CIG: |
Source |
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Keywords | TRANSFERASE / P38 / KINASE / INHIBITOR COMPLEX / PHOSPHORYLATION / SERINE/THREONINE-PROTEIN KINASE / HYDROLASE / ACETYLATION / PROTEIN TYROSINE PHOSPHATASE / INHIBITORS / HYDROLASE/HYDROLASE INHIBITOR / PROTEASE / BLOOD COAGULATION / ACUTE PHASE / CALCIUM-BINDING / DISEASE MUTATION / GAMMA-CARBOXYGLUTAMIC ACID / GLYCOPROTEIN / KRINGLE / PLASMA / SERINE PROTEASE / VITAMIN K / HYDROLASE-HYDROLASE INHIBITOR COMPLEX / BLOOD COAGULATION-INHIBITOR / POLYMORPHISME / ZYMOGEN / SULFATION / ATP-BINDING / NUCLEAR PROTEIN / 38 MAP KINASE / INHIBITOR STRUCTURE / RIBONUCLEASE / INHIBITOR / ENDONUCLEASE / CDK2 / CELL CYCLE / FRAGMENT SCREENING |