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-Structure paper
Title | Ligand-induced distortion of an active site in thymidylate synthase upon binding anticancer drug 1843U89. |
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Journal, issue, pages | Nat. Struct. Biol., Vol. 2, Page 1095-1101, Year 1995 |
Publish date | Aug 15, 1995 (structure data deposition date) |
Authors | Weichsel, A. / Montfort, W.R. |
External links | Nat. Struct. Biol. / PubMed:8846221 |
Methods | X-ray diffraction |
Resolution | 1.95 Å |
Structure data | PDB-1tsd: |
Chemicals | ChemComp-BME: ChemComp-UMP: ChemComp-F89: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE (METHYLTRANSFERASE) / DUMP / 1843U89 |