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-Structure paper
Title | Design of non-nucleoside inhibitors of HIV-1 reverse transcriptase with improved drug resistance properties. 1. |
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Journal, issue, pages | J. Med. Chem., Vol. 47, Page 5912-5922, Year 2004 |
Publish date | Jun 9, 2004 (structure data deposition date) |
Authors | Hopkins, A.L. / Ren, J. / Milton, J. / Hazen, R.J. / Chan, J.H. / Stuart, D.I. / Stammers, D.K. |
External links | J. Med. Chem. / PubMed:15537346 |
Methods | X-ray diffraction |
Resolution | 2.6 - 2.9 Å |
Structure data | PDB-1tkt: PDB-1tkz: PDB-1tl1: PDB-1tl3: |
Chemicals | ChemComp-PO4: ChemComp-MG: ChemComp-H12: ChemComp-HOH: ChemComp-H16: ChemComp-H18: ChemComp-H20: |
Source |
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Keywords | TRANSFERASE / HIV-1 REVERSE TRANSCRIPTASE / AIDS / NNRTI / GW426318 / DRUG DESIGN / GW429576 / GW451211 / GW450557 |