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-Structure paper
Title | Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. Usa, Vol. 101, Page 16903-16908, Year 2004 |
Publish date | May 24, 2004 (structure data deposition date) |
![]() | Erlandsen, H. / Pey, A.L. / Gamez, A. / Perez, B. / Desviat, L.R. / Aguado, C. / Koch, R. / Surendran, S. / Tyring, S. / Matalon, R. ...Erlandsen, H. / Pey, A.L. / Gamez, A. / Perez, B. / Desviat, L.R. / Aguado, C. / Koch, R. / Surendran, S. / Tyring, S. / Matalon, R. / Scriver, C.R. / Ugarte, M. / Martinez, A. / Stevens, R.C. |
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Methods | X-ray diffraction |
Resolution | 2.1 - 2.2 Å |
Structure data | ![]() PDB-1tdw: ![]() PDB-1tg2: |
Chemicals | ![]() ChemComp-FE: ![]() ChemComp-HOH: ![]() ChemComp-H2B: |
Source |
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![]() | OXIDOREDUCTASE / phenylalanine catabolism / phenylalanine hydroxylase phenylketonuria mutant A313T in complex with cofactor analogue 7 / 8-dihydrobiopterin |