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-Structure paper
Title | Biochemical and Structural Characterization of (South)-Methanocarbathymidine that Specifically Inhibits Growth of Herpes Simplex Virus Type 1 Thymidine Kinase-Transduced Osteosarcoma Cells |
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Journal, issue, pages | J. Biol. Chem., Vol. 279, Page 32832-, Year 2004 |
Publish date | Apr 3, 2003 (structure data deposition date) |
Authors | Schelling, P. / Claus, M.T. / Johner, R. / Marquez, V.E. / Schulz, G.E. / Scapozza, L. |
External links | J. Biol. Chem. / PubMed:15163659 |
Methods | X-ray diffraction |
Resolution | 1.95 Å |
Structure data | PDB-1of1: |
Chemicals | ChemComp-SCT: ChemComp-SO4: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / THYMIDINE KINASE / ANTIVIRAL DRUG / ENZYME-PRODRUG GENE / KINASE / DNA SYNTHESIS / ATP-BINDING |