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-Structure paper
Title | Probing the ATP Ribose-Binding Domain of Cyclin-Dependent Kinases 1 and 2 with O(6)-Substituted Guanine Derivatives |
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Journal, issue, pages | J. Med. Chem., Vol. 45, Page 3381-, Year 2002 |
Publish date | May 17, 2002 (structure data deposition date) |
Authors | Gibson, A.E. / Arris, C.E. / Bentley, J. / Boyle, F.T. / Curtin, N.J. / Davies, T.G. / Endicott, J.A. / Golding, B.T. / Grant, S. / Griffin, R.J. ...Gibson, A.E. / Arris, C.E. / Bentley, J. / Boyle, F.T. / Curtin, N.J. / Davies, T.G. / Endicott, J.A. / Golding, B.T. / Grant, S. / Griffin, R.J. / Jewsbury, P. / Johnson, L.N. / Mesguiche, V. / Newell, D.R. / Noble, M.E. / Tucker, J.A. / Whitfield, H.J. |
External links | J. Med. Chem. / PubMed:12139449 |
Methods | X-ray diffraction |
Resolution | 1.3 - 2.1 Å |
Structure data | PDB-1gz8: PDB-1h0v: PDB-1h0w: |
Chemicals | ChemComp-MBP: ChemComp-HOH: ChemComp-UN4: ChemComp-207: |
Source |
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Keywords | TRANSFERASE / KINASE / PROTEIN KINASE / CELL CYCLE / PHOSPHORYLATION / CELL DIVISION / MITOSIS / INHIBITION / SERINE/THREONINE-PROTEIN KINASE / ATP-BINDING / 3D-STRUCTURE. / DRUG METABOLISM / MYCOBACTERIA / ISONIAZID / ARYLAMINE N-ACETYLTRANSFERASE / NAT / SERINE/THREONINE -PROTEIN KINASE |