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-Structure paper
Title | Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses. |
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Journal, issue, pages | J. Biol. Chem., Vol. 275, Page 5633-5639, Year 2000 |
Publish date | Jan 13, 2000 (structure data deposition date) |
Authors | Ren, J. / Diprose, J. / Warren, J. / Esnouf, R.M. / Bird, L.E. / Ikemizu, S. / Slater, M. / Milton, J. / Balzarini, J. / Stuart, D.I. / Stammers, D.K. |
External links | J. Biol. Chem. / PubMed:10681546 |
Methods | X-ray diffraction |
Resolution | 2.8 - 3 Å |
Structure data | PDB-1dtq: PDB-1dtt: |
Chemicals | ChemComp-FPT: ChemComp-HOH: ChemComp-FTC: |
Source |
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Keywords | HYDROLASE/TRANSFERASE / HIV-1 reverse transcriptase AIDS / non-nucleoside inhibitor / drug design / HYDROLASE-TRANSFERASE COMPLEX |