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Structure paper

TitleStructural plasticity of human leptin binding to its receptor LepR
Journal, issue, pagesHlife, Vol. 1, Page 115-123, Year 2023
Publish dateNov 27, 2023 (structure data deposition date)
AuthorsXie YF / Li X / Qi J / Shang G / Lu D / Gao GF
External linksHlife / Search PubMed
MethodsEM (single particle)
Resolution3.58 - 3.88 Å
Structure data

EMDB-38131, PDB-8x80:
Structure of leptin-LepR trimer with a small gap
Method: EM (single particle) / Resolution: 3.88 Å

EMDB-38132, PDB-8x81:
Structure of leptin-LepR trimer with a large gap
Method: EM (single particle) / Resolution: 3.77 Å

EMDB-38136, PDB-8x85:
Structure of leptin-LepR dimer
Method: EM (single particle) / Resolution: 3.58 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsCYTOKINE / cytokine receptor / hexamer / tetramer

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