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Structure paper

TitleAllosteric activation of preformed EGF receptor dimers by a single ligand binding event.
Journal, issue, pagesFront Endocrinol, Year 2022
Publish dateDec 1, 2020 (structure data deposition date)
AuthorsPurba ER / Saita EI / Akhouri RR / Ofverstedt LG / Wilken G / Skoglund U / Maruyama I
External linksFront Endocrinol / Search PubMed
MethodsEM (tomography)
Resolution15.0 Å
Structure data

EMDB-30714:
Unliganded EGFR average cluster 1
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30715:
Unliganded EGFR averaged cluster 2
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30716:
Unliganded EGFR averaged cluster 3
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30717:
Unliganded EGFR averaged cluster 4
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30719:
Unliganded EGFR averaged cluster 6
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30721:
Unliganded EGFR averaged cluster 7
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30722:
Unliganded EGFR averaged cluster 9
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30723:
Unliganded EGFR averaged cluster 8
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30724:
Unliganded EGFR averaged cluster 9
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30725:
Unliganded EGFR averaged cluster 10
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30726:
Unliganded EGFR averaged cluster 11
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30727:
Unliganded EGFR averaged cluster 12
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30728:
Unliganded EGFR averaged cluster 13
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30729:
Unliganded EGFR averaged cluster 14
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30730:
Unliganded EGFR averaged cluster 15
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30731:
Unliganded EGFR averaged cluster 16
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30732:
Unliganded EGFR averaged cluster 17
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30733:
Unliganded EGFR averaged cluster 18
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30734:
Unliganded EGFR averaged cluster 19
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30735:
Unliganded EGFR averaged cluster 20
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30737:
Unliganded EGFR averaged cluster 22
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30738:
Unliganded EGFR averaged cluster 23
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30739:
Unliganded EGFR averaged cluster 24
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30740:
Unliganded EGFR averaged cluster 25
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30741:
Liganded EGFR averaged cluster 1
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30742:
Liganded EGFR averaged cluster 2
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30743:
Liganded EGFR averaged cluster 3
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30744:
Liganded EGFR averaged cluster 4
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30745:
Liganded EGFR averaged cluster 5
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30746:
Liganded EGFR averaged cluster 6
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30747:
Liganded EGFR averaged cluster 7
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30748:
Liganded EGFR averaged cluster 8
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30749:
Liganded EGFR averaged cluster 9
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30750:
Liganded EGFR averaged cluster 10
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30751:
Liganded EGFR averaged cluster 11
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30752:
Liganded EGFR averaged cluster 12
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30753:
Liganded EGFR averaged cluster 13
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30754:
Liganded EGFR averaged cluster 14
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30755:
Liganded EGFR averaged cluster 15
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30756:
Liganded EGFR averaged cluster 16
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30757:
Liganded EGFR averaged cluster 17
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30758:
Liganded EGFR averaged cluster 18
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30759:
Liganded EGFR averaged cluster 19
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30760:
Liganded EGFR averaged cluster 20
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30761:
Liganded EGFR averaged cluster 21
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30762:
Liganded EGFR averaged cluster 22
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30763:
Liganded EGFR averaged cluster 23
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30764:
Liganded EGFR averaged cluster 24
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30765:
Liganded EGFR averaged cluster 25
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30862:
Unliganded EGFR averaged cluster 5
Method: EM (tomography) / Resolution: 15.0 Å

EMDB-30864:
Unliganded EGFR averaged cluster 21
Method: EM (tomography) / Resolution: 15.0 Å

Source
  • Homo sapiens (human)

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