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TitleCryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy.
Journal, issue, pagesTo Be Published
Publish dateDec 6, 2023 (structure data deposition date)
AuthorsAnandapadamanaban M / Hay IM / Perisic O / Williams RL
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.1 Å
Structure data

19056

8rcn

EMDB-19056, PDB-8rcn:
CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy.
Method: EM (single particle) / Resolution: 3.1 Å

Chemicals

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Target of Rapamycin / mTOR / Cancer-associated mutants

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