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TitleInter-domain synergy enables both DNA and RNA G-quadruplex unwinding by the DEAH-box helicase DHX36
Journal, issue, pagesTo Be Published
Publish dateJan 30, 2024 (structure data deposition date)
AuthorsBanco MT / Paul T / Jiang J / Myong S / Ferre-D'Amare AR
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.6 - 3.0 Å
Structure data

43547

8vv2

EMDB-43547, PDB-8vv2:
Cryo-EM Structure of DHX36 bound to a RNA G-quadruplex derived from the cMyc G-quadruplex, Class 1
Method: EM (single particle) / Resolution: 2.6 Å

43555

8vvd

EMDB-43555, PDB-8vvd:
Cryo-EM Structure of DHX36 bound to a RNA G-quadruplex derived from the cMyc G-quadruplex, Class 2
Method: EM (single particle) / Resolution: 3.0 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHydrolase/RNA / DEAH-Box Helicase / Helicase / G-quadruplex / RNA / Hydrolase-RNA complex / MOTOR PROTEIN/RNA / MOTOR PROTEIN / MOTOR PROTEIN-RNA complex

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