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Structure paper

TitleCrystal structure of Lyp and its complex with a selective inhibitor
Journal, issue, pagesTo be Published
Publish dateJun 19, 2007 (structure data deposition date)
AuthorsYu, X. / Sun, J.P. / He, Y.T. / Zhou, B. / Liu, S.J. / Zhang, Z.Y.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.8 - 3 Å
Structure data

PDB-2qcj:
Native Structure of Lyp
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-2qct:
Structure of Lyp with inhibitor I-C11
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-561:
6-HYDROXY-3-{(4R)-1-[4-(1-NAPHTHYLAMINO)-4-OXOBUTYL]-1,2,3-TRIAZOLIDIN-4-YL}-1-BENZOFURAN-5-CARBOXYLIC ACID

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PTPN22 / LYP / PTP

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